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IRF TRANSCRIPTION FACTORS
Descriptors Found:
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DeCS
Descriptor
English
:
Interferon Regulatory Factors
Descriptor
Spanish
:
Factores Reguladores del Interferón
Descriptor
Portuguese
:
Fatores Reguladores de Interferon
Synonyms
English
:
IRF Transcription Factors
Transcription Factors, IRF
Tree Number:
D12.644.360.024.302
D12.776.157.057.050
D12.776.260.504
D12.776.476.024.385
D12.776.930.332
Definition
English
:
A
family
of
transcription factors
that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to
control
GENE expression
. IRF
proteins
bind specific DNA sequences such as interferon-stimulated
response elements
,
interferon
regulatory
elements
, and the
interferon
consensus sequence.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50774
Unique Identifier:
D050835
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS